Acomplia is an anti-obesity drug that is used to help obese people lose weight and maintain weight-loss. Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the Rimonabant. Acomplia usage is one 20 mg tablet every day. Acomplia is used in the treatment of obesity and related conditions by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle. It switches off the same brain circuits that make people hungry when they smoke cannabis. Acomplia has also been shown to help in smoking cessation.